Komen spent $79 million in research on metastatic breast cancer research from 2006 to 2012, which represents 15 percent of total research investment during that time.
The past few years have yielded some promising treatments for women with metastatic breast cancer, Friese said. The U.S. Food and Drug Administration approved Perjeta (pertuzumab) and Afinitor (everolimus), drugs that been used for other cancers, this year. Halaven (eribulin mesylate) was approved in 2010 for late-stage breast cancer.
But approval for another drug, Avastin (bevacizumab), was revoked in 2011 after the FDA deemed it not safe or effective enough.
Komen spends 25 percent of the money raised on research; the rest goes to local communities. Over the past 30 years, that has translated into $740 million toward breast cancer research, says Dorothy Jones, vice president of marketing.
As for advertising, which some outsiders perceive as excessive), Komen spends less than 2 percent of raised funds on that, Jones said. There are some 120 affiliates of Komen, and they have partners that donate media services to the organization.
When awareness gets political
For Komen, 2008 was one of the strongest years, but the organization has felt the effects of the country's economic slump since then, with a decline of investment dollars reflective of the broader economy, Jones said.
Not to mention the controversy that brewed earlier this year when Komen decided to stop funding Planned Parenthood's breast cancer screening programs and then reversed that decision three days later. NPR reported in June that participation in several Komen races declined since the decision. In August, two of the organization's leaders left their posts.
Affiliations with certain companies has also attracted negative attention for the organization.
Komen accepted more than $4.2 million from KFC in 2010, earning a part of the sales of fried or grilled chicken buckets. KFC restaurants had served up special pink buckets that year, with 50 cents of each one going to Komen. This arrangement came under fire for promoting unhealthy foods that could potentially increase the risk of cancer.
But Komen drew the line with donations when the adult entertainment site Pornhub.com promised to give 1 cent for every 30 views of specific breast videos. Komen wrote a cease and desist order, Jones said, noting also that the website is apparently not based in the United States.
"It was an organization globally that we didn't feel aligned with our values, and (we) could not accept funds from them," Jones said. "When you can't verify the efficacy of those dollars, where they're coming from, we don't associate with those types of organizations."
The sexualization of breast cancer awareness is something that bothers Tory Zellick, 28, of Chico, Calif.
She took care of her mother during the final three and a half years of her battle with breast cancer. Zellick has been noticing awareness logos that feature pink ribbons between cleavage and actual breasts.
Zellick, author of "The Medical Day Planner: The Guide to Help Navigate the Medical Maze," appreciates that most people genuinely want to help. At the same time, she's disturbed by the idea that a sophomore boy in high school with raging hormones would be wearing a wristband with a slogan such as "save the boobies."
"One day he may remember this experience and have possibly have a clearer understanding of what breast cancer and breast cancer awareness is," she said. "I just would like to see more education with the process."
Pink can be positive
Melody Wasson, 33, of Springfield, Mo., is a big fan of awareness. She had breast cancer at 28 and found out she is a carrier for the BRCA 1 genetic mutation, an inherited trait that greatly increases the risk of developing the condition. She had a double mastectomy to decrease the chance of a recurrence in the healthy breast. Wasson blogs about her experience at My Fight Against Breast Cancer.
She knows that either or both of her young daughters could inherit the gene, but she doesn't want to get them tested this early in life -- it would only spark fear on her part. Instead, she'll inform them about what it means -- already her 6-year-old knows her mommy survived breast cancer.
"I want my daughter to full-on know what it means to be a survivor," she said. "I want her to know when she sees that pink ribbon what that means."
Awareness for Wasson means "being your own advocate" -- doing self-exams and making the decisions that are best for you if you get a diagnosis. She's active in the Breast Cancer Foundation of the Ozarks, an organization that provides financial assistance and emotional support to anyone affected by breast cancer, as well as education. She has participated in the Susan G. Komen Race for the Cure for the past four years.
For all of the women who speak out about their individual patient experiences, write blogs and clamor for more support and funding, and there are others who would rather deal with their disease in private, Friese said. Not everyone wants to be out in public advocating.
"There's probably a group of women for whom the prominence of the topic that is not something that they cherish," Friese said.
Wadsworth remembers in October of 2010, she didn't always want to be thinking about her cancer, but pink was everywhere, reminding her. "My body was different, my breast had huge scars, I was bald, my life was (a) whirlwind, I felt like I was completely out of control, I really had to have faith that everything happens for a reason," she wrote in an email.
Today, she loves awareness and feels well enough to help others in need. Working as a massage therapist, she donates a portion of every session this month to Caring Connections, a nonprofit organization that helped her during her battle with breast cancer.