First lady Michelle Obama worked out with trainers from "The Biggest Loser" at the White House as part of her national Let's Move! initiative. Take a look at other Presidential first ladies and the causes they have supported.
Rosalynn Carter Carter made a campaign promise to get her husband Jimmy to establish a council on mental health. This came to fruition once she was in the White House. Although she only had an honorary role with the council, she used her position to speak widely on mental illness.