The Tigers are gearing up to take on the Red Sox for game three of the series. The series is tied 1-1. It all kicks off Saturday at 7:15 p.m. at Comerica Park.
Doug Fister and the Tigers fell so far behind, even Miguel Cabrera couldn't bring them back.
Cabrera homered and had four hits, but Detroit lost to the Boston Red Sox 10-6 on Friday night. Shane Victorino homered and hit three singles, driving in five runs for the Red Sox.
Cabrera hit a three-run homer for Detroit, which nearly rallied from a 6-1 deficit but couldn't come through against Boston's bullpen. Jon Lester (7-4) allowed five runs and nine hits in 5 2-3 innings, winning for the first time in seven starts.
The Red Sox lost Thursday night in the ninth inning, but their bullpen held the Tigers to one run Friday.
Fister (6-5) allowed six runs and 11 hits in 3 1-3 innings.
"Doug wasn't at his sharpest, but he didn't get any luck, either," Tigers manager Jim Leyland said. "I'm not making any excuses for him, but when they hit the ball hard, and they did hit some hard, they got a hit, and when they didn't hit the ball hard, they still got a hit."
Andy Dirks also homered for Detroit.
Both teams came into the game amid upheaval in the bullpen after Andrew Bailey gave up a game-winning homer to Detroit's Jhonny Peralta on Thursday. The Tigers designated Jose Valverde for assignment Friday, and the Red Sox are giving Bailey a break from closing.
Boston got through the last 3 1-3 innings Friday with Junichi Tazawa, Craig Breslow and Andrew Miller. Koji Uehara would likely have closed if the game had been tighter.
The Red Sox lead Baltimore by two games in the AL East. Cleveland trimmed Detroit's AL Central lead to three.
Fister didn't strike out a single batter, and Boston found seemingly every hole on the diamond against him. The Red Sox led 2-1 before coming up with six straight hits off Fister in the fourth. Jacoby Ellsbury's two-run double made it 4-1, and Victorino followed with a two-run single.
"Bottom line: I didn't do my job tonight," Fister said. "They're a good lineup — put the ball in play and did what they needed to do to put up runs."
It was Victorino's first four-hit game since 2011. He opened the scoring with a solo homer in the first, although the Tigers tied it in the second on Brayan Pena's RBI single.
Dustin Pedroia's run-scoring groundout in the third gave Boston a 2-1 lead, and the Red Sox scored four more the following inning.
Detroit answered with four in the fifth. Dirks hit a solo shot, and Cabrera's 20th homer of the year made it 6-5 and upped his RBI total to 74.
"Probably throw the best changeup I've ever thrown in my life to a guy that's just on a whole other playing field," Lester said. "Wish he'd quit and go to a different league — make a league especially for him, I guess. I thought at first it was off the end, and apparently not."
Jose Iglesias tripled in the sixth and scored on a single by Victorino.
On Cabrera's third hit — a clean single to right in the seventh — Victorino tried to throw him out at first from the outfield. Cabrera beat the throw and appeared to laugh and yell something in Victorino's direction.
Victorino nearly had a fifth hit in the eighth. With the bases loaded and one out, Peralta fielded his slow chopper and tried unsuccessfully to get a force at home. Boston took an 8-5 lead on the play, but it was ruled a fielder's choice and not a hit.
That was the first of two close plays at the plate that went Boston's way in the eighth. The second came when Al Alburquerque threw a wild pitch and came home to cover the plate. Pena retrieved the ball, but Stephen Drew appeared to get his arm under Alburquerque's tag attempt, and the Red Sox took a 9-5 lead.
Boston added a run in the ninth thanks to an error by center fielder Avisail Garcia that allowed Drew to score from first on a single by Iglesias.
Miller pitched the ninth for Boston, his first appearance at Comerica Park since he was traded from Detroit to Florida after the 2007 season as part of the deal that brought Cabrera to the Tigers. He gave up a single to Cabrera and an RBI grounder by Prince Fielder.
NOTES: Boston signed C Jon Denney, their third-round draft pick this year. The Red Sox also agreed to terms with four other draft picks: LHPs Corey Littrell, Jake Drehoff and Gabe Speier and OF Jordon Austin. ... Detroit agreed to terms with two draft picks: LHP Kevin Ziomek and RHP Austin Kubitza. The Tigers also agreed to terms with C Chris Taladay, an undrafted free agent. ... Detroit RHP Max Scherzer (10-0) faces Boston RHP Allen Webster (0-1) on Saturday night.