The Tigers are hoping for a four-game sweep of the host Houston Astros on Sunday.
After a ninth-inning rally to knock off the Astros on Friday, Detroit rode Cabrera's two home runs and a 21-hit attack to a 17-2 rout Saturday, its eighth victory in nine games after a 10-10 start.
Cabrera had his 26th career multi-homer game and tied a career high with six RBIs Saturday, going 4-for-4 in the process.
He entered the game with a .205 average in 31 games against Houston, by far his lowest mark against any team.
The Astros have dropped five straight and nine of 10 overall.
Written by By SportsDirect Inc.