Braylon Mullins sank a desperation 3-pointer with 0.4 seconds left to give UConn an astonishing 73-72 victory over top-seeded Duke, earning the Huskies a spot in the Final Four after they rallied from a 19-point first-half deficit.

Caleb Foster returned from a broken foot and rescued Duke’s national title hopes, helping the top-seeded Blue Devils rally from a 10-point second-half deficit to beat St. John’s 80-75 and advance to the Elite Eight.

Siena flirted with pulling off an all-time shocking upset in March Madness when it faced No. 1 overall tournament seed Duke.

The top seeds in the NCAA Tournament are generally heavy favorites in their first-round games.

Isaiah Evans scored 20 points, Cameron Boozer made two free throws with 3.9 seconds to seal the game and No. 1 Duke defeated No. 10 Virginia 74-70 on Saturday night for its second straight Atlantic Coast Conference Tournament championship under coach Jon Scheyer and its third title in the past four years.

Christian Anderson scored 23 of his 27 points in the second half, including the tiebreaking free throw with 3.4 seconds left, and No. 19 Texas Tech rallied from 17 down to beat third-ranked Duke 82-81 at Madison Square Garden.

Cameron and Cayden Boozer spent their Thanksgiving in a very familiar place, with their father, Carlos, taking in every moment.

Cameron Boozer had 35 points and nine rebounds to help No. 4 Duke hold off No. 22 Arkansas for a wild 80-71 win.

Duke freshman big man Khaman Maluach is jumping to the NBA.