A jury in Georgia has ordered Monsanto parent Bayer to pay nearly $2.1 billion in damages to a man who says the company’s Roundup weed killer caused his cancer.

Lawsuits in California are seeking potential class-action damages from Dow Chemical and its successor company over a widely used bug killer linked to brain damage in children.

Bayer said it was also paying up $1.22 billion to settle two additional areas of intense litigation, one involving toxic chemical PCB in water, and one involving dicamba, another weedkiller. The company said the settlement over Roundup, which is made by its Monsanto subsidiary, involves about 125,000 filed and unfiled claims. In August, a California jury ordered Monsanto to pay $86.7 million to a couple claiming that Roundup Ready caused their cancers. Claimants will be required to provide proof their crop yields were damaged by dicamba, Bayer said. The company said it expects contributions from co-defendant BASF toward the dicamba settlement.