Ocasio-Cortez began airing a TV spot this week that underlines the importance of turnout in what's likely to be a low-turnout primary.
Caruso-Cabrera has cast Ocasio-Cortez as a divisive elitist who ignores the district, which also covers parts of the Bronx.
Caruso-Cabrera said that after Congress approved the coronavirus bill and the pandemic was ravaging New York, Ocasio-Cortez stayed in a luxury apartment in D.C. with a Whole Foods in the lobby."
Caruso-Cabrera, 51, has vulnerabilities in the overwhelmingly Democratic district.
The organization tangled with Ocasio-Cortez in a Texas primary in March, when she backed an unsuccessful liberal challenger to pro-business Democratic Rep. Henry Cuellar.