What will be the biggest health trends of 2021? The Better Health Market & Café in Michigan, which has 14 locations statewide, has the answers: 2021 health trends are sensible lifestyles focusing on immunity and wellness. What’s in:Immunity Lifestyles – Boosting immunity is good for metabolism and health. Anti-Inflammation Diets – Greens like spinach and kale; almonds, walnuts, salmon, tuna, berries, turmeric. Melatonin and Ashwaganda herbs are trending and said to help as is Omega-3 Fatty Acids in Flax and Fish supplements.