Here are 10 college football upset picks for this weekend's games

10 favorites that could lose this weekend

There are sure to be upsets that surprise us this weekend in college football. (WDIV)

The weekend is almost here, and that means more college football!

Some teams are starting conference play, while others are finishing up their nonconference schedule. While there are only two matchups between ranked teams, there are sure to be multiple upsets that rock the college football world.

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Here are 10 potential upsets that could happen this weekend:

No. 23 Utah vs. Arizona

Line: Utah - 3.5

What's an upset article without a little Friday special?

Utah enters conference play ranked almost by default. The Utes have knocked off three lesser opponents, including rival BYU, which struggles to get the ball past midfield, let alone into the end zone.

Arizona isn't one of the more impressive teams in the Pac-12, but the Wildcat offense has eclipsed the 60-point mark twice in three games and could be dangerous in a home night game. Welcome back, Pac-12 after dark!

No. 14 Miami (Fla.) vs. Toledo

Line: Miami -13.5

Miami is considered among the favorites in the ACC Coastal Division this season, but it's been a very unusual start to the season.

After destroying an FCS opponent in Week 1, Miami had its game at Arkansas State canceled and a rivalry battle at Florida State suspended due to Hurricane Irma and its aftermath.

It's been three weeks since Miami played a game, while Toledo has put together a solid Group of Five resume. The Rockets are 3-0 with a win at Nevada and a shootout victory over solid Group of Five opponent Tulsa.

Logan Woodside is one of the most dynamic quarterbacks that nobody knows about. He's already thrown for more than 1,000 yards in three games, including eight touchdowns and only one interception.

No. 5 USC vs. California

Line: USC -17.0

Southern Cal looked great in its biggest game against Stanford, but not against two lesser opponents.

Western Michigan hung with the Trojans into the fourth quarter, and Texas had a lead with less than a minute left in the game. USC hasn't played its best against weaker competition.

California already has a nice road win over North Carolina on its resume, and a nonconference win over Ole Miss. At home, the Bears have a fighting chance.

If Cal is going to pull this off, it'll have to be in a shootout. Sam Darnold will likely have his way with the Golden Bears defense.

No. 22 San Diego State vs. Air Force

Line: San Diego State -3.0

This game is a perfect recipe for an upset, as San Diego State comes off a huge victory against a ranked Power Five opponent.

Running back Rashaad Penny was ridiculous against Stanford, gaining 275 yards on 32 carries, catching five passes for 31 yards and scoring a touchdown. Penny is the latest in a line of stud running backs at San Diego State.

But the Aztecs better not take Air Force lightly. The Falcons are coming off a 10-win season and hung with Michigan at the Big House last weekend.

No. 4 Penn State vs. Iowa

Line: Penn State -13.0

There's a wide gap between Penn State and Iowa in terms of offensive talent, but you never know when the Hawkeyes will sneak up and bite a ranked team.

Penn State has played three games this season, and none of their opponents has a single victory over an FBS team. It's been one of the weakest schedules in the Power Five.

Now, James Franklin's first test of the season comes against an adequate Iowa team in a tough environment. It's never easy to win in Kinnick Stadium, especially with a 7:30 p.m. kickoff.

No. 7 Washington vs. Colorado

Line: Washington - 11.5

Perhaps the least shocking schedule news of the month is that Washington played three cupcakes to begin the season. For the second straight year, Washington played a trio of pushovers in the nonconference season, and now Pac-12 play begins with a rematch of last year's conference championship game.

Colorado isn't as talented as a year ago, but the Buffaloes are off to a 3-0 start against their own manageable schedule.

The Colorado defense locked down both of its previous FBS opponents, holding Colorado State and Texas State to three points each.

No. 20 Florida vs. Kentucky

Line: -1.5

Florida returned to action with a bang last weekend, beating rival Tennessee with a last-second Hail Mary. As the Gators come down from that high, they'd better not sleep on Kentucky.

It's been three decades since Kentucky beat Florida in football, so there's nothing fans want more than to put those talks to rest.

Kentucky proved it can compete last weekend when it went into South Carolina's house and left with a convincing 23-13 win. The Gamecocks appeared to be on the rise, so it was a solid win for Kentucky.

Florida has more talent, but the questions at quarterback will also leave the Gators susceptible to an upset.

No. 12 Florida State vs. NC State

Line: Florida State - 12.5

If Florida State drops its first home game against North Carolina State, it will essentially be an upset of circumstance.

After battling Alabama in the season opener, the Seminoles learned they had lost starting quarterback Deondre Francois for the season, leaving their offense in limbo.

On top of the injury, Florida State's second game was canceled, so after the suspended game against Miami, it hasn't played in three weeks.

N.C. State hasn't been impressive this season, but the talent on the defensive line could be a tough matchup for a new starting quarterback.

Notre Dame vs. Michigan State

Line: Notre Dame - 3.0

Before the season, Notre Dame and Michigan State were complete unknowns after disappointing 2016 seasons. Since then, they've both rebounded.

Notre Dame earned style points with its 29-point thrashing of Boston College last weekend. The Irish look like a legitimate threat to win eight or nine games this season.

But Michigan State is tough at home, and Mark Dantonio orchestrated a big win over Notre Dame last season. The Spartans have had two weeks to prepare for this game, and they'll be ready.

Stanford vs UCLA

Line: Stanford -7.0

Stanford returns home this weekend after brutal performances in back-to-back road games. The Cardinal was trounced by USC and upset in San Diego State to fall below .500.

UCLA is coming off a road loss of its own -- a 48-45 slugfest in Memphis. Jim Mora's defense is dreadful, but with Josh Rosen at the helm, UCLA can beat anybody.

Like many of the games on this list, it'll have to be a shootout for an upset to happen, because UCLA's defense is a sieve.


About the Author:

Derick is the Lead Digital Editor for ClickOnDetroit and has been with Local 4 News since April 2013. Derick specializes in breaking news, crime and local sports.