Detroit Lions coach Dan Campbell says center Cade May will be out for significant time because of a wrist injury.

Rookie TreVeyon Henderson had a 100-yard kickoff return for a touchdown to open the game, quarterback Drake Maye added a 5-yard touchdown run and the New England Patriots beat the Washington Commanders 48-18 in the exhibition opener for both teams.

The New England Patriots have agreed to trade quarterback Joe Milton III to the Dallas Cowboys.

The Jacksonville Jaguars are AFC South champions for the first time in five years.

The Pittsburgh Steelers followed a stumbling first half with a strong final 30 minutes to beat Dallas 16-3 in the first NFL preseason game in two years.