The crash happened just before 7 p.m. on June 1.
Authorities said the victim, from Pontiac, was driving a 2011 Buick Regal and turning left turn onto northbound Martin Luther King Jr. Boulevard from Michigan Avenue when she was hit by a 2007 BMW 750.
The driver in the BMW -- a 48-year-old man from Mt. Clemens -- then struck a 2009 Dodge Journey waiting to turn left onto westbound Michigan Avenue.
The 46-year-woman in the Buick was pronounced dead at the scene. The 21-year-old driver in the Dodge Journey was treated at the scene.
The 48-year-old man in the BMW was taken to a hospital and treated for minor injuries. He is in custody under the suspicion of driving under the influence.
Deputies said alcohol and speed appeared to be factors, and a search warrant was completed for a blood draw.
The crash is under investigation.
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